Exemestane and how it works
Exemestane helps lower down the levels of estrogen in a woman’s body. It is effective in slowing down the growth of breast tumors which rely on estrogen to develop. It is generally used as a treatment for breast cancer patients who are already in the postmenopausal period. Breast cancer patients who have had surgery use exemestane to help heal their condition. It is mostly prescribed to women who have undergone radiation or surgery yet was unsuccessful. The medicine is most commonly known as Aromasin. Before taking the medicine, you must ensure that you are not allergic to it to prevent serious illnesses. If you are pregnant or a woman who hasn’t reached menopause yet, it is not advisable to take this medication. In order to ensure that it is safe for you to take, inform if your doctor if you have kidney or liver disease. One of its side effects is having a decreased bone mineral density. As a result, a patient may be at a higher risk of having osteoporosis. Exemestane is also known to cause birth defects in pregnant women.
It’s important to use a pregnancy test first to ensure that the results are indeed negative. Women who are in the postmenopausal period, estrogen relies on the change of sex hormones from androgen to estrogen. Aromatase is needed in order for this change to occur. Exemestane blocks and inhibits the enzyme. As a result, it effectively reduces the amount of estrogen in the woman’s body which slows down the growth of cancer cells.
The exact dosage of exemestane that should be used would depend on your doctor’s prescription. It’s important to follow the instructions of your doctor accurately. You shouldn’t take a smaller or bigger amount than prescribed. Generally, exemestane is taken once a day after a meal. Patients are usually prescribed 25mg a day. Although you can take your medicine with whichever meal you prefer, it’s recommended to take it at the same time every day. This ensures that you’ll be able to remember taking it regularly. If in case you forget to take it during one of the meals in the day, take it after eating a snack instead. If in case you completely forget to take it for an entire day, only take the prescribed daily amount the next day. Do not take two doses of exemestane to make up for the missed dosage. In order to enjoy its full benefits, make sure to take it regularly. Before you run out of the medicine, have your doctor refill your prescription.
If you experience any side effects from taking the medicine, you should consult a doctor immediately. Its most common side effects include difficulty breathing, hives and swelling of the tongue, throat, lips or face. You should immediately get medical assistance if you experience unusual bone pain, shortness of breath from mild exertion, swelling in your hands and feet, chest pain or sudden weakness and headaches. You may also experience problems with speech, vision or balance. Other common side effects of exemestane include joint pain, hot flashes, severe headaches, insomnia, nausea and increased sweating. Keep in mind that your doctor provided you this medication because he has calculated that you will be experiencing more benefits of the medicine compared to its side effects. Therefore, if you experience any of these serious side effects you must contact your doctor immediately. An extreme allergic reaction to exemestane is very rare. However, if you begin experiencing rashes, severe dizziness, swelling, or difficulty breathing you must call your doctor for medical advice immediately.
It’s important to let your doctor know if you are allergic to the medicine before taking it. You should also let your doctor know about any other allergies you may have to make sure that you wouldn’t experience major side effects. Exemestane contains inactive ingredients which may cause various types of allergic reactions. One of the first steps you have to do before taking it is informing your doctor about your complete medical history. This is especially important if you have experienced high cholesterol levels, blood clots, stroke, bone problems like osteoporosis and osteopenia, high blood pressure, heart attack, liver problems and kidney problems. The medicine may cause you to feel tired or dizzy. According to recent research, patients who are taking exemestane are more prone to experience a heart disease. The medicine will not affect the estrogen levels produced by the ovaries for pre-menopausal women. Its safety and effectiveness have not yet been established for women who haven’t reached their menopause period yet. It is also known that exemestane increases the risk of stomach problems such as an ulcer. If you are currently taking Non-Steroidal Anti-Inflammatory Medications (NSAIM) or you’ve had a stomach problem in the past, inform your doctor before taking the medication. The safety and effectiveness of exemestane for children has not yet been established.
HOW TO GET THE MOST FROM YOUR TREATMENT
To help ensure that your medication is working, it’s important to have regular doctor’s appointments all throughout your treatment. Your doctor will be able to check your progress and adjust the dosage of exemestane according to your needs. Since the medicine lowers down female hormone levels in your body, it can cause your bones to become weak. It is recommended to take bone density tests in order to ensure that your bones are in good condition. These tests are usually done before and during your treatment. If you will be having a dental treatment or operation in the near future, make sure to let them know that you are currently taking exemestane.
HOW THE MEDICATION WORKS
Exemestane belongs to a group called antineoplastics which is a group of cancer-fighting medications. It is the most common medication prescribed to breast cancer patients who are past their menopause period. The system of these patients is no longer responding to tamoxifen which is should provide increased health benefits. Tamoxifen is also part of the antineoplastic group of medications. The medicine is used to treat advanced breast cancer situations in postmenopausal women. If a patient has already undergone an anti-estrogen treatment yet cancer still continues to develop, exemestane is prescribed. It fights off cancer cells by inactivating an enzyme called aromatase. Once it attaches to the enzyme, it effectively prevents it from providing estrogen to the body. Estrogen helps certain types of breast cancer cells to increase, grow and survive. Exemestane is available under multiple brand names and is also available in several different forms.
HOW IT IS USED IN BODYBUILDING/FITNESS
Bodybuilders who use steroids can benefit from using exemestane or Aromasin. This is because estrogen is unwanted by-product of steroid usage. Certain tissues of the male body contain the aromatase enzyme which is mainly responsible for turning testosterone and other male hormones into female hormones such as estradiol or estrogen. An increased amount of female hormones in a man’s body can cause several negative side effects. The most common ones include water retention and breast tissue growth. In general, bodybuilders make use of a variety of drugs and compounds to aid them in their workouts. To be able to successfully combat these negative side effects, it’s important to make sure that estrogen levels cannot multiply exponentially. Estrogen is a female hormone and it shouldn’t be seen in excess in males. Bodybuilders will be able to use the medicine to inhibit the aromatase enzyme. By taking Aromasin, bodybuilders will be able to ensure that testosterone and other steroids will not be converted into female hormones such as estrogen. An Aromatase Inhibitor (AI) is a compound which effectively prevents the aromatase enzyme to create estrogen. Although there are several methods which makes use of AI, exemestane or Aromasin is the most popular one among bodybuilders. It is considered to be a suicidal inhibitor which makes it the best choice compared to other AIs. Exemestane effectively binds with the aromatase enzyme and then immediately disables it permanently by destroying it.
HOW IT WORKS
Aromasin is referred to as a steroidal AI because it ensures that your lipids will not be negatively affected. Exemestane isn’t liver toxic either. This means that it could be used for an extended period of time without having any harmful side effects. Therefore, it is a great alternative compared to another run on cycles looking at a fitness standpoint. It will not hurt your gains on cycle unlike other types of AIs. It also lowers down the SHBG levels in your body which increase the ratio of testosterone. It can also help bodybuilders have a very positive impact on their gains. Aromasin is able to effectively block aromatization which inhibits estrogen production. According to recent studies, exemestane has very beneficial effects to steroid users, such as bodybuilders. There are plenty of anabolic steroids which can increase estrogen levels because of the aromatase process. When there is excess water retention in the body, the person will experience an increased risk of developing high blood pressure.
It’s EFFECTS FOR BODYBUILDERS
In a therapeutic point of view, Aromasin effectively blocks the aromatase enzyme which then prohibits the cancer cells actively from feeding off the hormone which it needs to survive. It’s important to understand the functions and traits of Aromasin for anabolic steroid users. Excessive estrogen levels may cause water retention and gynecomastia. Testosterone is the primary aromatizing steroid. However, testosterone which has been derived from Dianabol may cause a strong estrogenic reaction. The Boldenone hormone aromatizes at 50% the testosterone rate. This amount is still capable of causing an estrogen buildup for some people. For 19 nortestosterone anabolic steroids, it will always include all forms of Trenbolone and Nandrolone. Nandrolone aromatizes at 20% the testosterone rate. However, it also carries a strong progestin element. As a result, it can provide a good amount of estrogenic activity in males. Trenbolone isn’t capable of aromatizing at all. However, it has a strong progestin element which may aid in the development of gynecomastia. Regardless of whatever type of steroid is being used, exemestane or Aromasin offers protection for bodybuilders to prevent unwanted estrogenic effects.
Aromasin is easily accessible and widely available in the prescription market. The original exemestane tablet can only be found under the Aromasin brand. It is usually administered in the tablet form. In recent years, there have been several research chemical laboratories who have been developing their own version of exemestane. Legally, these laboratories are allowed to produce their own versions of the medicine. They have started to develop it in liquid form which contains Letrozole and Anastrozole. However, most people still prefer the tablet version. There is also an abundance of online websites which sell exemestane under the Aromasin brand. Normally, you would need a prescription to purchase it. Besides for breast cancer treatment purposes, Aromasin is rarely prescribed for any other health condition. By purchasing Aromasin online, you wouldn’t have to worry about the prescription.
In conclusion, Aromasin is a very effective and powerful AI which is beneficial for both breast cancer patients and bodybuilders. It has several benefits which are valuable to the health and well being of the aforementioned individuals. If you are a bodybuilder who wants to try Aromasin for the first time, make sure to think about the cholesterol issues it may provide. It is strongly suggested for anabolic steroid users to take Aromasin together with a low dosage of Nolvadex. This will help ensure the person’s protection from experiencing any cholesterol issues in the future. Nolvadex is an anti-estrogen which performs the role of estrogen in the liver. As a result, it helps promote healthy cholesterol levels. No matter how you prefer to take Aromasin, keep in mind that you should have a healthy lifestyle to support it. By practicing a cholesterol friendly lifestyle and diet, you’ll be able to reap the full benefits of the medicine. Avoid eating saturated fats and foods which are high in sugar.
Sol Ruiz heads our Research Digest department. He graduated from the New York University where he obtained his Master’s Degree in Public Health.