What is Ipamorelin?
Ipamorelin is an amino acid chain (peptide) that is classified as a GHRP (growth hormone releasing peptide) which is similar to GHRP 2, GHRP 6 and Hexarelin.
This peptide is known as the mildest GHRP in comparison to the ones mentioned before. But that also means it has the least side effects and is the most versatile GHRP that can be used in any AAS, SARMs and peptide stack for extra gains. It can also be used to increase low GH levels when natural GH secretion has been inhibited by long-term abuse of synthetic GH. Ipamorelin increases growth hormone secretion without the negative side effects associated with the others in its category such as increased cortisol or prolactin.
Unless you’re a hobbyist bodybuilder, you’ve heard of HGH. Even though there is a big association between HGH and steroids, HGH is actually a hormone naturally produced by the body. In the Human Growth Hormone world, Ipamorelin has been deemed the safest. It lies in the same category of GHRPs as Hexarelin. It works in two ways. First, by stimulating the pituitary gland promoting the production of additional growth hormone. Then, it reduces effects of Somatostatin. This is the hormone that tells the pituitary glands to stop producing more growth hormone.
Is it safe?
Yes, Ipamorelin, like all GHRPs’ are very safe to use for both short and long periods of time. No users have reported health issues after use of Ipamorelin, although if you have a tumor or cancerous growth, please do not use any Ipamorelin.
5 Benefits of Ipamorelin
Here are 5 ways in which Ipamorelin is beneficial to bodybuilders and athletes.
1. Anti-aging effects
Biologically, it’s impossible to prevent aging. But, we can slow the process. Ipamorelin is used in age management therapies. Here’s how it works. As we age, bone generation slows exponentially. (This is why fractures in younger people). Wear and tear repair lowers with age too. Ipamorelin induces the liver into producing growth factor 1 hormone (IGF-1) in a way similar to how insulin is produced. This hormone then triggers body tissue formation and bone regeneration. In a study conducted at the University of California, 28 healthy adults were administered growth hormone. They were all men aged fifty years and above. After some time, tests revealed that most of them experience enhanced collagen deposits. This study suggested that Ipamorelin could prevent aging. They had notably higher bone masses. In addition to stronger joints and connective tissues, certain studies reported that those who were administered with Ipamorelin had improved skin tones.
2. Increased lean muscle mass growth
Perhaps this is the most pronounced reason why bodybuilders go for Ipamorelin shots. Many bodybuilders are turning to Ipamorelin for solid muscle. This peptide is usually taken 30 – 45 minutes before they hit the gym. When administered in the optimal conditions, Ipamorelin users gain about 30% more lean muscle in their first 4 months. The difference in muscle growth is noticeable in the first two months of its usage. However, the amount of muscle you will put on is dependent on many factors. It is affected by how long you work out each day, your age, diet, genetics, lifestyle, sleep etc. I could go on and on but you get the idea. The 30% increase in lean mass above is experienced by a bodybuilder eating a protein-rich diet and has more than 7 hours of consistent sleep each night. If you ask any bodybuilder, their greatest motivation is pushing past their previous muscle size. Ipamorelin will give you just that.
3. Faster weight loss
Many obese individuals have inhibited human growth hormone levels. Others do not respond well to this stimulus. For successful weight loss to occur, lipids have to be broken down. This is known as the lipolysis process. The growth hormone accelerates break down of fats into glycerol and fatty acids. With dietary restrictions, Ipamorelin therapy affects how anabolic actions take place. In return, the individual loses weight. In Europe and America where obesity is prominent, many women are using exercise in addition to extreme diets to keep their weight at bay. Many of them are turning to science. Ipamorelin might be the answer. However, HGH on its own won’t be effective in cutting weight. It has to be accompanied by low-calorie diets as well as proper exercise.
4. Healthy skin, nails and hair growth.
Due to age-related factors, our skin loses its elasticity and may even start sagging. Thinner hair and grey hair are common too. These are all effects of decreased human growth hormone levels. As you are aware, Ipamorelin promotes the generation of this hormone. Several studies on this hormone have shown that there is improved skin texture when this hormone is administered. From reducing wrinkles to improving our energy levels, its health effects cannot be overlooked. It is common knowledge that glowing skin is smooth and hydrated. Skin is the largest body organ. It’s no surprise that it is the most affected by growth hormone declination. Wrinkles, cellulite and age spots are all associated with low levels of this hormone. Many men and women notice these skin benefits in their sixth month of Ipamorelin injections. Some of them even report that they look anywhere between ten and twenty years younger. It is worth noting that these benefits are only experienced by individuals with this hormone’s deficiency. Hair growth begins when keratin is produced by keratinocytes. At the base of hair follicles, hair cells are formed. These hair cells (known as hair bulbs) continuously divide and grow. They then form the hair shaft. For healthy hair growth, these cells have to be nourished by blood vessels. Ipamorelin assists in this cell regeneration process. For strong, thick and healthy hair, new cells have to be generated frequently. As we age, the pigment cells responsible for melanin formation in hair follicles slowly die. Now you know how gray hair appears. Nail formation works in the same way.
5. Lowering blood pressure
High blood pressure is common among seniors. Human growth hormone restoration in the body has proven to be effective in controlling blood pressure and other cardiovascular-related illnesses. A Swedish doctor noted that growth hormone deficient patients were twice likely to suffer from high blood pressure than their healthy counterparts of the same age and gender. Individuals with growth hormone deficiency had increased resistance to insulin as well as low levels of healthy cholesterol. These symptoms are common in diabetes patients. Even in obese adults, lower cases of hypertension (high blood pressure) were recorded when they were subjected to Ipamorelin therapy. According to many physicians, healthy growth hormone levels play a major role when it comes to healthy hearts and healthy blood vessels. With Ipamorelin, individuals experience muscle gains, reduced fat levels, positive vibes, and healthier skin. Like all other supplements, Ipamorelin isn’t a silver bullet. There are no “miracle” drugs. It has its own place in promoting human growth hormone. While you can use it in both the bulking and cutting phase, Ipamorelin is effective and no users have reported adverse side effects up-to-date. There are reports of mild headaches though.
What can I expect from Ipamorelin?
With Ipamorelin, you can expect the usual results from increased growth hormone.
These include Increased muscle gains, reduction of fat, overall positive mood, and better skin health.
Like all peptides, they are not a “magic” drug, but they have their place either as a standalone PED or in a stack which uses SARMs such as S4, LGD-4033 or with Anabolics and other Peptides.
What can I use it for?
Ipamorelin is a very versatile peptide, commonly used in AAS, SARM and peptide stacks for extra muscle gains and fat loss, sometimes both as a recomp drug.
The link below will get you to the official supplier which has the best price available on the as of December 2018
Are there any side effects?
The only side effects reported from Ipamorelin include a headache and/or a slight headrush feeling when taking too much. It is expected that users start at the lower end of the common dosing range and build up from there.
What should I use Ipamorelin with?
As said before, it is versatile in the fact it can be used as a recomp drug, or for cutting and bulking.
So if you are planning on a recomp, you are best combining it with SARMs such as GW-505156 (increased fat loss), LGD-4033 (extra muscle gain) and S4 (recomp drug as well). Adding other peptides to this is also a great idea. The following peptides are useful for cutting:
- IGF-1 LR3
- HGH Fragment
The Following Peptides are useful for adding muscle and is a good idea to add to any stack where you are trying to add muscle:
- IGF-1 LR3
- Follistatin 344
Storage and Dosage information
When it is in powder form, it’s smart to store it in a freezer for long periods of time (around 12 months). But once reconstituted with either Bacteriostatic water or acetic acid, it should be in a refrigerator for up to 5 weeks. The typical dosage for Ipamorelin is approximate 200-300mcg, taken 2-4 times a day. You can use these for an infinite amount of time and does not need a PCT if by itself.
Summary of Ipamorelin
- Increases Lean Body mass
- Reduces body fat
- Helps with sleep, and helps with a positive mood
- Has anti-aging properties
- Improves recovery time
- Great to stack with SARMs and Peptides
Sol Ruiz heads our Research Digest department. He graduated from the New York University where he obtained his Master’s Degree in Public Health.