What is Ketotifen?
Ketotifen drops are an antihistamine and a cell stabilizer. It functions by preventing the secretion of chemicals from cells which cause allergic reactions. Generally prescribed under the brand name Zaditor, ketotifen is mostly used for treating allergy-related symptoms. These symptoms include disturbances in the eye and are caused by allergens such as dust, pollen dander, mold etc. While the body naturally reacts to these allergens by secreting histamine which can be uncomfortable to patients.
Before using Ketotifen you should inquire about a few factors and make sure that you avoid any complication that the use of the drug may lead to. Listed below are a few factors that you should consider before using ketotifen.
Allergic: The most important factor that one should consider if he is allergic to any of the chemicals used in the ketotifen drops. And in case you fall under the group, you should immediately get in contact with your doctor.
Heart And liver Condition: While using ketotifen you should do regular checkups on organs like the liver and the heart. Any major change should be immediately reported to the doctor or discussed with the pharmacist.
Medication: There are multiple medicines that interact with the drug and can prove fatal for the user. Anyone using ketotifen should discuss the issue of other medicines they are under and their effect on ketotifen with their doctors. And in case a user finds out that he is in the danger zone he should look for alternatives or stop using at least one of those drugs.
Prior To Using Ketotifen
Ketotifen is capable of triggering a variety of medical conditions in a user. The importance of the user discussing his medical conditions with his doctor or a trusted pharmacist before starting ketotifen is immense. The following are a few of those medical conditions that the drug can trigger,
- Pregnancy: When it comes to pregnancy risks, the drug is not a reliable one. A disappointing score of Cby the American Food and Drug Administration in the category of pregnancy risk speaks volumes. There are many chances of ketotifen causing harm to a growing fetus. Though it is still not clear if the drug can pass through breastmilk, it is advisable for breastfeeding mothers to avoid the use of ketotifen. Mothers should also make sure that the drug remains out of reach of the kids as ketotifen can be dangerous to anyone under the age of three.
- Allergic: Apart from being allergic to the ingredients of the drug the user can also be allergic to the type of the medicine or food items or even other substances. It is recommended for a normal person to get a test done to determine the substance his body allergic before starting to use ketotifen.
- Medication: With the existence of various medical conditions, multiple drugs exist in the medical world. And many of those drugs can actively react with ketotifen and cause serious damage to the user. Thus it is very important for anybody using the drug or even planning for it to discuss all the drugs they use on a regular basis with their doctors or at least a trusted pharmacist.
- Organ Problems: Somebody with a history of problems with their heart or liver should stay away from the use of the drug and even people suffering from low electrolyte count should also refrain from it.
How Should You Use Ketotifen?
While using the drug in the form of drops you should be careful about handling the drug with clean hands. While applying the drop the user needs to stretch the upper eyelid, you can try to use your index finger to hold it in a pouch. Apply a drop in the eyeballs, close your eyelids and immediately apply pressure with your fingers to spread the medicine all over the region. One must apply the pressure gently and direct it towards the interior corners of the eyes. While you can use a clean cloth or a cotton tissue to wipe away the excess medicine, you should be careful about not touching the concerned area.
The user should not blink for about a minute or two after applying the drop and it is also advisable for him to wash off his hands to remove any bit of the drug that might linger on it. Apart from the mentioned factor, one has to be careful about a few more factors such as not applying the drop to any other part of the body than the eyes.
Ketotifen is a serious drug and should not be used for rashes that occur due to the use of contact lenses. When using contact lenses, one should be careful enough while using the drug. Not only does one need to take of their lenses while taking the drug but also needs to keep the lenses away till about ten minutes of use.
General Facts About Ketotifen
It is quite normal for ketotifen to cause a mild stinging sensation in the eyes when it is applied to the eyes but you should immediately get in contact with your doctor it the sensation stays.Ketotifen is a very specific drug and should not be used for any condition if not advised by a doctor. The drop form of the drug can be dangerous if it is swallowed and in case you have taken the drop form of drug orally, you need to immediately contact the poison control center or a hospital. The safety of ketotifen among infants is still an unknown fact and it is not advisable to use the drug on any child under the age of three.
Pregnancy & Breastfeeding
Studies have already shown us that the drug can be fatal for a developing fetus and a user needs to get in touch with her doctor if she turns pregnant while using this drug. Though it is still not known if the medicine can pass through the breast milk to the kids but it is not advisable for breastfeeding mothers to use ketotifen.
Ketotifen Side Effects
Apart from the desired impacts, users might have to face some undesirable side effects for using ketotifen. If any of these symptoms do occur, they may require medical attention.
Some of the less common side effects include a cough, diarrhea, fever, illness, headache, joint pain, nausea, runny nose, shivering, chills, sore throat, sweating fits, insomnia, and vomiting.
Some of the rare side effects of this drug include abdominal pain, blisters, bloody urine, convulsions, dark urine, rash, frequent urination, temporary loss of consciousness, breath odor, yellow skin and bloody vomit.
A portion of the symptoms that can occur due to using ketotifen may not require medical attention. As your body acclimates to the pharmaceutical amid treatment these effects may just vanish. Your doctor can educate you regarding approaches to diminish or keep some of these symptoms and thus it is very important to consult a doctor if one faces side effects from the drug. In case any of the side effects linger on, it is a matter of concern and should be dealt with properly with the help of a doctor.
A few of those minor side effects are the bloody nose, weight gain, drowsiness, dryness of mouth, nervousness, eyelid swelling, swelling of the limbs, nosebleeds etc.
Allergic Conjunctivitis (Adults) :
For allergic conjunctivitis in adults, two or three drops for each eye is enough and the dose has to be repeated a couple of times in the day. It is mainly for the treatment of allergic reaction from dust, ragweed, grass, dander etc.
Allergic Conjunctivitis (Minors) :
The drug should only be used in minors above the age of three as it is dangerous for infants. A single drop for one eye and one can repeat the dose for a couple of times in a day but should be separated by at least eight to twelve hours
Ketotifen & Bodybuilders
While available in the ophthalmic form, the H-1 antihistamine is also available in the oral form which is specially designed to prevent asthma attacks and can also work for insomnia or as an appetite stimulant. It is on for a drug used against asthma attacks has side effects like weight gain and appetite stimulation. Apart from the mentioned benefits, the drug protects the cell lining of the abdomen, the intestines and the gut from toxic infections. Skin problems like acne can also be treated with ketotifen and it ca eve be helpful for diseases like edema.
As the drug is able to stimulate the appetite of the user it is quite common among bodybuilders across the globe. Studies have shown that Ketotifen can block TNF-alpha hormones which is an advantage to the bodybuilders as these hormones can immensely lower testosterone levels accompanied with IGF-1 levels. And as long and hard working out schedules can accelerate the secretion of TF-alpha, ketotifen is a very important steroid to the bodybuilders. TNF-alpha also reduces the glucose intake levels of muscles and the condition is often called insulin resistance.
First introduced to the bodybuilding world by Dan Duchaine, who proposed its utilization for upregulation of Beta – Receptors. Long after his passing, I made sense of that Benadryl would work for a similar reason, and Ketotifen was to a great extent replaced by the easily available Benadryl.
It is, in any case, due to the late Karl Hoffman that we stumbled upon the utilization of Ketotifen for decreasing TNF-an and for its conceivable use in PCT. He spearheaded this idea, and it has proved to be extremely useful as an against catabolic, however, it’s cost makes it a bit restrictive for use in up-controlling Beta-Receptors.
Ketotifen & Clenbuterol
Clenbuterol is a beta 2 agonist which has a constrained anabolic impact amid its initial few days of utilization and a while later is typically used to battle fat. When consumed in higher dosages, it can be catabolic to muscles and must be cycled on an alternate basis, changing it every two weeks, otherwise, the beta 2 receptors that clean ties can turn to saturate an even start to regulate.
Ketotifen is better than clenbuterol as it upregulates the beta-receptors including the beta 2s that clen employes. For whatever length of time that you are taking ketotifen, it will keep on cleaning these receptors, never permitting them to downregulate – even while on an overwhelming clen cycle. That implies you need to keep on taking clenbuterol inconclusively without cycling off to recover the receptors. 2-3 mgs of ED can upregulate and even seriously close down receptors inside seven days.
It implies that you don’t require as much clen to get similar advantages. It appears u can take around forty to fifty percent less clenbuterol and it is similarly powerful. Studies show that it likewise builds the number of receptor destinations on the surface of the cell, permitting more clenbuterol to connect and maybe this is the purpose of the expanded viability. Ketotifen likewise appears to diminish the sides of clen including a bad case of nerves.
Ketotifen & ECA
A superior use for ketotifen is using it with the ECA stack. While the thermogenic impact of ephedrine is not as intense as clenbuterol in light of the fact that it doesn’t have a high receptor partiality, and it is not constrained to beta-2 receptors. Truth be told it appears to affect the beta 3 receptors in a good way too, and over a portion of ephedrine, an impact is from beta-3 incitement. Clenbuterol has no impact on beta 3 in any way. So by keeping the beta 2 receptors up, ketotifen can permit the advantages of ceaseless beta 2 and beta 3 incitement from ephedrine.
How Should Bodybuilders Take Ketotifen?
There has still been no study that determines the right amount of dosage of ketotifen when bodybuilders are concerned. The person who discovered ketotifen recommended ten milligrams of ED which can often be too much and result in sleepiness. For first-timers, three to four milligrams is normally perfect and does the required job. It must be mentioned that excess usage does not show any adverse effect other than making the user tremendously hungry. While the drug can be taken at different times of a day, it can also be taken all at once.
Apart from people suffering from epilepsy the drug is totally safe for everyone. Even when the drug is taken in excess it hardly causes any toxic reactions. Though the drug does have some temporary side effects such as,
- Frequent hunger
- Dry mouth
- Weight Gain
Sol Ruiz heads our Research Digest department. He graduated from the New York University where he obtained his Master’s Degree in Public Health.